The overarching objective of this plan for 2016-2019 is to strengthen national and regional public health responses with respect to the prevention, treatment, and control of viral hepatitis and reductions in viral hepatitis-related morbidity, disability, and mortality in Member States in the Americas. The Plan of Action is based on the following strategic lines of action: a) Promoting an integrated comprehensive response. b) Fostering equitable access to preventive care. c) Fostering equitable access to clinical care. d) Strengthening strategic information. e) Strengthening laboratory capacity to support diagnosis, surveillance, and a safe blood supply.